Fasciculin



Fasciculins (FASs) are toxins produced by the snake green mamba. FASI and FASII are known to bind to acetylcholinesterase (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, i.e. the crystal structure of Fasciculin 1 (1fas).

Fasciculin
1fas – FASI

1fsc - FASII

FAS+ AChE
2x8b, 1b41 – FASII+hAChE – human

1f8u - FASII+hAChE (mutant)

1ku6, 1mah - FASII+mAChE – mouse

1fss - FASII+AChE – Torpedo californica